Kevin Sussman (actor, writer, comedian, The Big Bang Theory) discusses his anxiety surrounding performing and reveals his process for tricking his brain into redirecting anxious thoughts. Mayim and Kevin reminisce about their shared experiences on the set of The Big Bang Theory and examine the differences between Kevin and his character, "Stuart Bloom." Kevin shares the advice George Clooney and Gary Shandling gave to him about combating anxiety and the body mechanics of the Alexander Technique he uses to manage habitual physical tension. Mayim breaks down the physiological symptoms and evolutionary advantages of anxiety, the science and cultural aspects of crying, and ways to avoid the trap of rumination. They discuss the benefits and side effects of anxiety medication and natural coping methods, and Mayim ends the episode with advice for managing anxiety when trying to fall asleep in the latest installment of Ask Mayim Anything.